Volume : 12, Issue : 1, JAN 2026

PREPARATION AND APPLICATIONS OF HETEROCYCLIC COMPOUNDS IN ORGANIC CHEMISTRY

AFRAH MOHAMED SHARAF

Abstract

Heterocyclic compounds are an essential class of organic molecules containing rings with one or more heteroatoms, such as nitrogen, oxygen, or sulfur. Their unique structures and diverse reactivity make them key building blocks in pharmaceuticals, agrochemicals, and advanced materials. This paper explores the preparation methods and applications of heterocyclic compounds, beginning with a discussion of their classification based on ring size and type of heteroatom. Classical synthetic approaches such as the Paal–Knorr and Fischer indole syntheses are reviewed alongside modern techniques like microwave-assisted synthesis, green chemistry methods, and biosynthetic pathways. The chemical behavior of heterocycles is also examined, including aromaticity, substitution reactions, and tautomerism. Practical applications are highlighted across several fields, with examples from drug development, crop protection, electronic materials, and industrial processes. Despite their wide utility, challenges remain in achieving selectivity and sustainability. The paper concludes with future directions, emphasizing the role of green chemistry and innovative design in expanding the potential of heterocyclic compounds in science and technology.

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IESRJ

International Educational Scientific Research Journal

E-ISSN: 2455-295X

International Indexed Journal | Multi-Disciplinary Refereed Research Journal

ISSN: 2455-295X

Peer-Reviewed Journal - Equivalent to UGC Approved Journal

Peer-Reviewed Journal

Article No : 11

Number of Downloads : 37

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